简介：Hepatology Digest：how do you think the clinical practice of proteinase inhibitors ? Will the side effects affect its clinical use? 《国际肝病》：您怎样看待蛋白酶抑制剂在临床上的应用以及这些药物的副作用？ Professor Kwo: the proteinase inhibitors will likely be the first small molecular medicine approved for the treatment of genotype 1 hepatitis C. This will greatly improve the cure rate of hepatitis C. Thus far all of the proteinase inhibitors studied to date do have more side effects than peglated interferon and Ribovirin together which also have side effects.